This is a self-applied treatment programme for small animal phobia (mice, spiders and cockroaches). This programme uses VR scenarios developed especially for this type of phobias. It simulates a large number of real scenarios, in such a way that the patient can be exposed to and practice diverse situations related to the fear of these animals. The programme has an evaluation protocol that makes it possible to evaluate each person’s situation in an individualized way. Supported by self-help materials developed specifically for this treatment, the patient can face diverse situations, obtaining continuous feedback, and as they are overcome, their difficulty increases. Various studies have provided data that show the high level of efficacy of this programme (Baños, Quero, Botella, & García-Palacios, 2007; Botella et al., 2008).